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        "hgvsWellDefined": "NP_001341547.1:p.[Arg446_Gln448delinsGlySerSerThr;Ile450delinsLeuArg;Glu452_Glu453delinsArgPro;Thr455_Leu456delinsGlnAla;Gly458_Val463delinsArgValLysCysLeuAla;Gly465_Ile467delinsPheGlnThr;Asn469Gly;Trp471_Lys472delinsGlyLeu;Thr474_Val475del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720520"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2440,
          "referenceAllele": "C",
          "start": 2439
        }
      ],
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        "NM_001354619.2:c.1336del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341548.1:p.Arg446GlyfsTer?",
        "hgvsWellDefined": "NP_001341548.1:p.[Arg446_Gln448delinsGlySerSerThr;Ile450delinsLeuArg;Glu452_Glu453delinsArgPro;Thr455_Leu456delinsGlnAla;Gly458_Val463delinsArgValLysCysLeuAla;Gly465_Ile467delinsPheGlnThr;Asn469Gly;Trp471_Lys472delinsGlyLeu;Thr474_Val475del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720521"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "start": 2078
        }
      ],
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        "NM_001354620.2:c.1765del"
      ],
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        "hgvsWellDefined": "NP_001341549.1:p.[Arg589_Gln591delinsGlySerSerThr;Ile593delinsLeuArg;Glu595_Glu596delinsArgPro;Thr598_Leu599delinsGlnAla;Gly601_Val606delinsArgValLysCysLeuAla;Gly608_Ile610delinsPheGlnThr;Asn612Gly;Trp614_Lys615delinsGlyLeu;Thr617_Val618del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720522"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2109,
          "referenceAllele": "C",
          "start": 2108
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      ],
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      "geneNCBI_id": 4292,
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      "hgvs": [
        "NM_001354621.2:c.1036del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341550.1:p.Arg346GlyfsTer?",
        "hgvsWellDefined": "NP_001341550.1:p.[Arg346_Gln348delinsGlySerSerThr;Ile350delinsLeuArg;Glu352_Glu353delinsArgPro;Thr355_Leu356delinsGlnAla;Gly358_Val363delinsArgValLysCysLeuAla;Gly365_Ile367delinsPheGlnThr;Asn369Gly;Trp371_Lys372delinsGlyLeu;Thr374_Val375del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720523"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2222,
          "referenceAllele": "C",
          "start": 2221
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      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354622.2:c.1036del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341551.1:p.Arg346GlyfsTer?",
        "hgvsWellDefined": "NP_001341551.1:p.[Arg346_Gln348delinsGlySerSerThr;Ile350delinsLeuArg;Glu352_Glu353delinsArgPro;Thr355_Leu356delinsGlnAla;Gly358_Val363delinsArgValLysCysLeuAla;Gly365_Ile367delinsPheGlnThr;Asn369Gly;Trp371_Lys372delinsGlyLeu;Thr374_Val375del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720524"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2131,
          "referenceAllele": "C",
          "start": 2130
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354623.2:c.1036del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341552.1:p.Arg346GlyfsTer?",
        "hgvsWellDefined": "NP_001341552.1:p.[Arg346_Gln348delinsGlySerSerThr;Ile350delinsLeuArg;Glu352_Glu353delinsArgPro;Thr355_Leu356delinsGlnAla;Gly358_Val363delinsArgValLysCysLeuAla;Gly365_Ile367delinsPheGlnThr;Asn369Gly;Trp371_Lys372delinsGlyLeu;Thr374_Val375del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720525"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1841,
          "referenceAllele": "C",
          "start": 1840
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
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      "hgvs": [
        "NM_001354624.2:c.985del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341553.1:p.Arg329GlyfsTer?",
        "hgvsWellDefined": "NP_001341553.1:p.[Arg329_Gln331delinsGlySerSerThr;Ile333delinsLeuArg;Glu335_Glu336delinsArgPro;Thr338_Leu339delinsGlnAla;Gly341_Val346delinsArgValLysCysLeuAla;Gly348_Ile350delinsPheGlnThr;Asn352Gly;Trp354_Lys355delinsGlyLeu;Thr357_Val358del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720526"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1739,
          "referenceAllele": "C",
          "start": 1738
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354625.2:c.985del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341554.1:p.Arg329GlyfsTer?",
        "hgvsWellDefined": "NP_001341554.1:p.[Arg329_Gln331delinsGlySerSerThr;Ile333delinsLeuArg;Glu335_Glu336delinsArgPro;Thr338_Leu339delinsGlnAla;Gly341_Val346delinsArgValLysCysLeuAla;Gly348_Ile350delinsPheGlnThr;Asn352Gly;Trp354_Lys355delinsGlyLeu;Thr357_Val358del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720527"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1836,
          "referenceAllele": "C",
          "start": 1835
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354626.2:c.985del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341555.1:p.Arg329GlyfsTer?",
        "hgvsWellDefined": "NP_001341555.1:p.[Arg329_Gln331delinsGlySerSerThr;Ile333delinsLeuArg;Glu335_Glu336delinsArgPro;Thr338_Leu339delinsGlnAla;Gly341_Val346delinsArgValLysCysLeuAla;Gly348_Ile350delinsPheGlnThr;Asn352Gly;Trp354_Lys355delinsGlyLeu;Thr357_Val358del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720528"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2068,
          "referenceAllele": "C",
          "start": 2067
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354627.2:c.985del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341556.1:p.Arg329GlyfsTer?",
        "hgvsWellDefined": "NP_001341556.1:p.[Arg329_Gln331delinsGlySerSerThr;Ile333delinsLeuArg;Glu335_Glu336delinsArgPro;Thr338_Leu339delinsGlnAla;Gly341_Val346delinsArgValLysCysLeuAla;Gly348_Ile350delinsPheGlnThr;Asn352Gly;Trp354_Lys355delinsGlyLeu;Thr357_Val358del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720529"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1996,
          "referenceAllele": "C",
          "start": 1995
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354628.2:c.1966del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341557.1:p.Arg656GlyfsTer?",
        "hgvsWellDefined": "NP_001341557.1:p.[Arg656_Gln658delinsGlySerSerThr;Ile660delinsLeuArg;Glu662_Glu663delinsArgPro;Thr665_Leu666delinsGlnAla;Gly668_Val673delinsArgValLysCysLeuAla;Gly675_Ile677delinsPheGlnThr;Asn679Gly;Trp681_Lys682delinsGlyLeu;Thr684_Val685del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720530"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1990,
          "referenceAllele": "C",
          "start": 1989
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354629.2:c.1960del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341558.1:p.Arg654GlyfsTer?",
        "hgvsWellDefined": "NP_001341558.1:p.[Arg654_Gln656delinsGlySerSerThr;Ile658delinsLeuArg;Glu660_Glu661delinsArgPro;Thr663_Leu664delinsGlnAla;Gly666_Val671delinsArgValLysCysLeuAla;Gly673_Ile675delinsPheGlnThr;Asn677Gly;Trp679_Lys680delinsGlyLeu;Thr682_Val683del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720531"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1924,
          "referenceAllele": "C",
          "start": 1923
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007127",
      "geneNCBI_id": 4292,
      "geneSymbol": "MLH1",
      "hgvs": [
        "NM_001354630.2:c.1894del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001341559.1:p.Arg632GlyfsTer?",
        "hgvsWellDefined": "NP_001341559.1:p.[Arg632_Gln634delinsGlySerSerThr;Ile636delinsLeuArg;Glu638_Glu639delinsArgPro;Thr641_Leu642delinsGlnAla;Gly644_Val649delinsArgValLysCysLeuAla;Gly651_Ile653delinsPheGlnThr;Asn655Gly;Trp657_Lys658delinsGlyLeu;Thr660_Val661del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720532"
    }
  ],
  "type": "nucleotide"
}