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        {
          "allele": "T",
          "end": 454,
          "endIntronDirection": "+",
          "endIntronOffset": 854,
          "referenceAllele": "C",
          "start": 454,
          "startIntronDirection": "+",
          "startIntronOffset": 853
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      ],
      "gene": "http://reg.genome.network/gene/GN000186",
      "geneNCBI_id": 100,
      "geneSymbol": "ADA",
      "hgvs": [
        "NM_001322050.2:c.73+854C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001308979.1:n.73+854C>T"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS718065"
    },
    {
      "@id": "http://reg.genome.network/allele/PA916026506",
      "coordinates": [
        {
          "allele": "T",
          "end": 537,
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      ],
      "gene": "http://reg.genome.network/gene/GN000186",
      "geneNCBI_id": 100,
      "geneSymbol": "ADA",
      "hgvs": [
        "NM_001322051.2:c.445C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001308980.1:p.Arg149Trp",
        "hgvsWellDefined": "NP_001308980.1:p.Arg149Trp"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS718066"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 537,
          "referenceAllele": "C",
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      "gene": "http://reg.genome.network/gene/GN000186",
      "geneNCBI_id": 100,
      "geneSymbol": "ADA",
      "hgvs": [
        "NR_136160.2:n.537C>T"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS730959"
    }
  ],
  "type": "nucleotide"
}